Zometa (zoledronovoyi acid), and production ...

There are two main competitors in the drug Fosamax bisphosphonates in the market. While Fosamax Merck, by far the best selling and most widely proposed osteoporosis drug on the market, Aredia Novartis International AG and Zometa popular alternatives. These two drugs are very similar, but differ in Dosage. Aredia (pamidronat sodium) was first approved by the Administration Food and Drug Administration in 1991 and used to treat hypercalcemia, Paget's disease and some forms of cancer such as multiple myeloma. It works by preventing bone resorption, or process by which some cells break down bone to release minerals that some types of cancer can cause. For nearly 15 years, he was popular for the treatment of several conditions, but by 2005, the popular and medical opinion of a class of drugs bisphosphonates began to change. After installation suggests serious bone complications associated with the first delivered in 2004, Novartis and FDA informed dental health professionals May 18, 2005 about a possible link between Aredia and necrosis of the jaw (ONJ). Warning informed dentists that patients undergoing Aredia treatment should avoid invasive dental procedures and that they should be aware of the primary symptoms of ONJ. According to reports collected by officers of Novartis, 875 developed ONJ between December 2002 and 2005. Most of these patients receiving chemotherapy and steroid treatment, two conditions that may involve the development of ONJ. Unfortunately, Aredia can increase the number of complications that can arise even from simple procedures, including free teeth, gums swollen, or tissues of the mouth, just do not heal. Zometa (zoledronovoyi acid) and of Novartis, is believed to be 100 times more powerful than Aredia. Doctors prescribe it in smaller doses for a short period of time, and it has been successful in treating hypercalcemia, Paget's disease and multiple myeloma. Unfortunately, it is more dangerous than Aredia, because it is more powerful. FDA and Novartis have warned dentists and other oral health professionals about a possible link between Zometa and jaw necrosis. Unfortunately, 875 people have been injured between 2002 and 2005, some of them suffer terrible injuries that required removal of part or all of the jaw. Zometa was first introduced to the market in 2001 and quickly earned more than $ 1 billion in sales. Bisphosphonates and complex drugs, and as such can cause a number of side effects. Some of the most common side effects include gastrointestinal disorders, esophageal erosions, electrolyte disturbances, as well as hip fractures. In addition, patients suffering from chronic renal failure release the drug more slowly than others, so doctors should exercise particular caution when prescribing bisphosphonates. If you or someone you know has taken bisphosphonates drug that causes adverse side effects, you should contact a lasix 40 meq lawyer immediately. You may be entitled to monetary compensation for injuries, but if you wait too long, you may lose your right to a remedy. Contact a dedicated and experienced defective drug lawyer and get started on the path to justice today. .